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Research project

A Tavassoli - CRUK Programme Foundation Award

Staff

Lead researchers

Professor Ali Tavassoli

Professor of Chemical Biology
Connect with Ali

Email: A.Tavassoli@soton.ac.uk

Research outputs

Identification and development of cyclic peptide inhibitors of Hypoxia Inducible Factors 1 and 2 that disrupt hypoxia-response signaling in cancer cells
Andrew T. Ball, Soran Mohammed, Cyrielle Doigneaux, Reece M. Gardner, James W. Easton, Steven Turner, Jonathan W. Essex, Garry Pairaudeau & Ali Tavassoli, 2024, Journal of the American Chemical Society, 146(13), 8877–8886
DOI: 10.1021/jacs.3c10508
Type: article
Hypoxia drives the assembly of the multi-enzyme purinosome complex
Cyrielle Doigneaux, Anthony Pedley, Ishna N Mistry, Monika Papayova, Stephen Benkovic & Ali Tavassoli, 2020, The Journal of Biological Chemistry, 295(28), 9551-9566
DOI: 10.1074/jbc.RA119.012175
Type: article
Reprogramming the transcriptional response to hypoxia with a chromosomally encoded cyclic peptide HIF-1 inhibitor
Ishna Mistry & Ali Tavassoli, 2017, ACS Synthetic Biology, 6(3), 518-527
DOI: 10.1021/acssynbio.6b00219
Type: article