Research project

Continued Brain Tumour Research Funding For BRAIN UK (2022 - 2025)

Lead researchers:

Professor Delphine Boche
Research funder:

Brain Tumour Research
Status:

Active

Staff

Lead researchers

Professor Delphine Boche

Professor of Neuroimmunopathology

Research interests

Neuroimmunology and neurodegeneration
Immunophenotyping immune cells
Human brain pathology

Connect with Delphine

Email: D.Boche@soton.ac.uk

Research outputs

Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma

Imran Noorani, Magnus Haughey, James Nicoll, Emma Norton & Delphine Boche, 2025, Cancer Discovery

Type: article

Spatial transcriptomics reveals microglial mechanisms driving amyloid-β clearance in immunized Alzheimer’s disease patients

Lynn van Olst, Brooke Simonton, Alex Edwards, Anne Forsyth, Jake Boles, Pouya Jamshidi, Thomas Watson, Nate Shepard, Talia Krainc, Benney M.R. Argue, Ziyang Zhang, Joshua Kuruvilla, Lily Camp, Mengwei Li, Jeanette L. Norman, Joshua Cahan, Robert Vassar, Jinmiao Chen, Rudolph L. Castellani, James A.R. Nicoll, Delphine Boche & David Gate, 2025, Nature Medicine, 31, 1604-1616

DOI: 10.1038/s41591-025-03574-1

Type: article

The spectrum of IDH- and H3-wildtype high-grade glioma subgroups occurring across teenage and young adult patient populations

R. Pereira, A. Mackay, Y. Grabovska, A. Bradley, T. Bloom, J. Nicoll & D. Boche, 2024, Clinical Cancer Research

Type: article