Research project

Core Capability for Chemistry Research in Southampton - Brown - EPSRC

Lead researchers:

Professor Richard Brown
Other researchers:

Professor Gill Reid
Research funder:

EPSRC
Status:

Not active

Staff

Lead researchers

Professor Richard Brown

Professor of Organic Chemistry

Research interests

Organic synthesis
Total synthesis of natural products
Asymmetric synthesis

Connect with Richard

Email: R.C.Brown@soton.ac.uk

Other researchers

Professor Gill Reid

PROFESSOR OF CHEMISTRY

Research interests

Synthetic inorganic chemistry
Design and synthesis of new macrocyclic and multidentate ligands involving donor atoms from G…
Coordination chemistry with s-, p-, d- and f-block metal ions

Connect with Gill

Email: G.Reid@soton.ac.uk

Research outputs

In pursuit of larger lipophilicity enhancement: an investigation of sugar deoxychlorination

2025, Organic & Biomolecular Chemistry, 23(11), 2586-2589

DOI: 10.1039/D5OB00037H

Type: article

Practicable syntheses of electroluminescent ionic 2,2′-bifluorenes

Edward H. Jackman, Oliver J. Ward, Yi Li, Katie L. Court, Robert C. Carroll, Simon J. Coles, Stephen P. Beeby, Isabelle Chataigner, Julien Legros & David C. Harrowven, 2024, European Journal of Organic Chemistry, 27(48)

DOI: 10.1002/ejoc.202400976

Type: article

De Novo enantioselective synthesis of hexafluorinated d-glucose

Sébastien Depienne, Clement Q Fontenelle, Mark Light, Kristof Van Hecke & Bruno Linclau, 2024, Journal of Organic Chemistry, 89(19), 14291-14304

DOI: 10.1021/acs.joc.4c01724

Type: article

Exploring 2-sulfonylpyrimidine warheads as acrylamide surrogates for targeted covalent inhibition: a BTK story

Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E. Wales, Raji E. Joseph, Amy H. Andreotti, Jonathan C. Strefford, Graham Packham & Matthias G.J. Baud, 2024, Journal of Medicinal Chemistry, 67(16), 13572-13593

DOI: 10.1021/acs.jmedchem.3c01927

Type: article

Conformational analysis of 1,3-difluorinated alkanes

William G. Poole, Florent Peron, Stephen J. Fox, Neil Wells, Chris Kriton Skylaris, Jonathan W. Essex, Ilya Kuprov & Bruno Linclau, 2024, Journal of Organic Chemistry, 89(12), 8789–8803

DOI: 10.1021/acs.joc.4c00670

Type: article

Quantitative analysis of 2D EXSY NMR spectra of strongly coupled spin systems in transmembrane exchange

Dmitry Shishmarev, Clement Q. Fontenelle, Bruno Linclau, Ilya Kuprov & Philip W. Kuchel, 2023, ChemBioChem, e202300597

DOI: 10.1002/cbic.202300597

Type: article

Rapid investigation of the effect of binary and ternary solvent gradient mixtures on reaction outcomes using a continuous flow system

Dawid Drelinkiewicz, Tom J.A. Corrie & Richard J. Whitby, 2023, Reaction Chemistry and Engineering

DOI: 10.1039/d3re00464c

Type: article