About
With expertise in regenerative medicine, physiology, engineering, orthopaedics, prosthetics and orthotics, rehabilitation and assistive technologies, epidemiology and clinical trial design, we aim to improve lives by delivering improved treatments, increasing the speed to market of musculoskeletal-focused technology and training the next generation of scientists and engineers.
The population across the globe is living longer, which brings a number of healthcare challenges, especially in musculoskeletal health. The burden of age-related disease and injury is rising rapidly, having a detrimental impact on people’s quality of life and increasing the costs of healthcare provision. Loss of muscle mass and function is the leading reason for loss of independence in later life, and causes impaired mobility, falls, fractures, physical disability, increased insulin resistance and associated co-morbidities, and mortality. The number of hip fractures is expected to rise to 6.3 million by 2050 and the number of diabetic lower limb amputations has now risen to 7,000 per year in the UK and over 70,000 in the USA.
The University is working to meet these challenges by creating networks of experts working in interdisciplinary musculoskeletal health research to develop new technologies, interventions and practices that will have a positive effect on people’s lives:
- FortisNet is an interdisciplinary research network of clinical, academic and industrial partners that aims to develop products and services to transform musculoskeletal health. Launched in 2016, we have fostered over 50 new collaborations with other universities from across the UK, the NHS and industry. We have developed courses with national partners to help innovators understand how to bring medical technologies to market, and through investment in interdisciplinary studentships we are working to dissolve discipline boundaries, to train a new generation of life scientists and engineers for the benefit of society.
- MyAge (Muscle resilience across the life course: from cells to society) is one of eleven UK Ageing Networks, funded by the Biotechnology and Biological Sciences Research Council and Medical Research Council. Led by the Institute for Life Sciences, together with partners from Birmingham, Nottingham and Imperial, the network will guide the future of muscle resilience research through roadmap development and interdisciplinary collaboration.
Muscle analytics for elite sports
PhD Researcher Dr Devon Lewis is developing a new type of wearable muscle sensor to accelerate injury recovery and performance training in elite sports.
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Preventing the transmission of non-communicable disease risk between generations
Research from the Developmental Origins of Health and Disease Centre demonstrates how the diet and lifestyle choices of prospective parents and pregnant mothers can affect the long-term health of their children.
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Using nanoclay gel to regrow, repair and replace damaged cells
Southampton researchers have developed an innovative medical clay that can be used to apply regenerative medicine to patients with musculoskeletal conditions.
People, projects and publications
People
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Doctor Matthew Blunt
Associate ProfessorAccepting applications from PhD studentsEmail: M.D.Blunt@soton.ac.ukTel: +44 2381206671 -
Professor Matthew Garner
Professor of Psychology & Affective NeuroscienceNeuropsychological mechanisms and treatment targets in anxiety disorders.
Accepting applications from PhD studentsEmail: M.J.GARNER@soton.ac.ukTel: +44 23 8059 5926 -
Professor Matthew Loxham
ProfessorEmail: M.Loxham@soton.ac.ukTel: +44 23 8059 9673 -
Doctor Matthew Rose-Zerilli
Associate ProfessorCancer prevention
Innate immunity
Tumour microenvironment
Accepting applications from PhD studentsEmail: M.J.Rose-Zerilli@soton.ac.ukTel: +44 2381205163 -
Professor Matthew Terry
Professor of Molecular Plant BiologyChloroplast development and retrograde signalling to the nucleus
Accepting applications from PhD studentsEmail: mjt@soton.ac.ukTel: +44 23 8059 2030 -
Doctor Matthias Baud
Associate ProfessorChemical Biology
Medicinal Chemistry
Protein Sciences
Cancer
Accepting applications from PhD studentsEmail: M.Baud@soton.ac.ukTel: +44 23 8059 4081 -
Professor Max Crispin
Director (Institute for Life Sciences)Viral Glycobiology
Therapeutic Antibodies
Accepting applications from PhD studentsEmail: Max.Crispin@soton.ac.ukTel: +44 23 8059 4268 -
Doctor Melissa Andrews
Associate Professorspinal cord injury
gene therapy
axonal regeneration
stem cells
Accepting applications from PhD studentsEmail: M.R.Andrews@soton.ac.ukTel: +44 23 8059 2432 -
Professor Michael Boniface
Professor of Information TechnologyArtifical intelligence for health systems
Human centred interactive systems
Email: M.J.Boniface@soton.ac.ukTel: +44 23 8059 8866 -
Professor Michael Hornberger
Professor of Applied Dementia ResearchPersonalised cognition in preclinical and clinical dementia
Accepting applications from PhD studentsEmail: M.Hornberger@soton.ac.uk
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Related research institutes, centres and groups
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Bioengineering Science Research Group
We apply engineering principles to the fields of biology and healthcare. -
Engineering Materials and Surface Engineering Group
Our research activities are often multidisciplinary involving collaborations with other research groups, Universities and industry partners. -
national Centre for Advanced Tribology at Southampton (nCATS)
We specialise in tribology which is the science of friction, wear and lubrication of surfaces that come in to contact in motion. -
Smart Electronic Materials and Systems
Our interests range from nano-scale biological sensors to complete sensor systems. -
NIHR Southampton Biomedical Research Centre
The NIHR Southampton Biomedical Research Centre takes new discoveries, treatments and technologies into the clinic, using unique tools, facilities and world-changing expertise. -
MRC Lifecourse Epidemiology Centre
We study the determinants of musculoskeletal and metabolic disease throughout the lifecourse.