Publications

Browse our publications catalogue to learn about our research.
Fc-γ receptor-mediated crosslinking co-defines the immunostimulatory activity of anti-human CD96 antibodies
Anne Rogel, Fathima M Ibrahim, Stephen Thirdborough, Florence Renart-Depontieu, Charles Birts, Sarah Buchan, Xavier Preville, Emma King & Aymen Al-Shamkhani, 2022, JCI Insight, 7(19)
DOI: 10.1172/jci.insight.158444
Type: article
FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms
Alexander Patrick Simpson, Ali Roghanian, Robert James Oldham, Claude Chan, Christine Penfold, Sonya James, Yury Bogdanov, Christopher Mockridge, Hyung Kim, Tatyana Inzhelevskaya, Stephen Beers & Mark Cragg, 2022, Cell Reports, 40(3)
DOI: 10.1016/j.celrep.2022.111099
Type: article
Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma
Charles N. Birts, Constantinos Savva, Stéphanie A. Laversin, Alicia Lefas, Jamie Krishnan, Aron Schapira, Margaret Ashton-Key, Max Crispin, Peter W.M. Johnson, Jeremy P. Blaydes, Ellen Copson, Ramsey I. Cutress & Stephen A. Beers, 2022, Scientific Reports, 12(1)
DOI: 10.1038/s41598-022-11696-6
Type: article
Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering
Franziska Heckel, Anna Turaj, Hayden Fisher, Claude Chan, Michael Marshall, Osman Dadas, Christine Penfold, Tatyana Inzhelevskaya, Christopher Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen Beers, Mark Cragg & Sean Lim, 2022, Communications Biology, 5(1), 1-15
DOI: 10.1038/s42003-022-03182-6
Type: article
LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation
Muchaala Yeboah, Charys Papagregoriou, Des C. Jones, Hak Chan, Guangan Hu, Justine McPartlan, Christopher Mockridge, Ivo Tews, Martin Glennie, Stephen Thirdborough, Mark Cragg & Ali Roghanian, 2020, JCI Insight, 5(18)
DOI: 10.1172/jci.insight.141593
Type: article