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Dr Sonya James

Specialist Microscopy Technician

Connect with Sonya

Email: sonya.james@soton.ac.uk

Tel: +44 23 8059 1024

ORCID
Publications Biography
Publications Biography

Publications

21 publications
Page 1 of 3
FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRs
Alexander P. Simpson, Robert J. Oldham, Kerry L. Cox, Martin C. Taylor, Sonya James, Yury Bogdanov, Martin J. Glennie, Bjorn Frendeus, Mark S. Cragg & Ali Roghanian, 2025, Clinical and Experimental Immunology, 219(1)
DOI: 10.1093/cei/uxaf015
Type: article
Reducing affinity as a strategy to boost immunomodulatory antibody agonism
Xiaojie Yu, Christian Orr, H.T. Claude Chan, Sonya James, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Jonathan W. Essex, Ivo Tews, Martin J. Glennie & Mark Cragg, 2023, Nature, 614(7948), 539-547
DOI: 10.1038/s41586-022-05673-2
Type: article
ATM regulates differentiation of myofibroblastic cancer-associated fibroblasts and can be targeted to overcome immunotherapy resistance
Massimiliano Mellone, Klaudia Piotrowska, VENTURI GIULIA, Lija James, Aleksandra Bzura, Maria-Antoinette Lopez, Sonya James, Chuan Wang, Matthew Ellis, Christopher Hanley, Josephine F. Buckingham, Kerry Cox, Gareth Hughes, Viia Valge-Archer, Emma King, Stephen Beers, Vincent Jaquet, George Jones, Natalia Savelyeva, A. Emre Sayan, Jason Parsons, Stephen Durant & Gareth Thomas, 2022, Cancer Research, 82(24), 4571-4585
DOI: 10.1158/0008-5472.can-22-0435
Type: article
Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
Emily Rose Webb, Julia Moreno Vicente, Alistair Easton, Silvia Lanati, Martin Taylor, Sonya James, Emily L. Williams, Christine Penfold, Stephen Beers, Juliet Gray & Vikki English, 2022, iScience, 25(9)
DOI: 10.1016/j.isci.2022.104995
Type: article
FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms
Alexander Patrick Simpson, Ali Roghanian, Robert James Oldham, Claude Chan, Christine Penfold, Sonya James, Yury Bogdanov, Christopher Mockridge, Hyung Kim, Tatyana Inzhelevskaya, Stephen Beers & Mark Cragg, 2022, Cell Reports, 40(3)
DOI: 10.1016/j.celrep.2022.111099
Type: article
HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy
Khiyam Hussain, Rena Liu, Rosanna C G Smith, Kri T J Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L S Cleary, Robert J Oldham, Russell B Foxall, Sonya James, Steven G Booth, Tom Murray, Lekh N Dahal, Chantal E Hargreaves, Robert S Kemp, Jemma Longley, James Douglas, Hannah Markham, Serena J Chee, Richard J Stopforth, Ali Roghanian, Matthew J Carter, Christian H Ottensmeier, Bjorn Frendéus, Ramsey I Cutress, Ruth R French, Martin J Glennie, Jonathan C Strefford, Stephen M Thirdborough, Stephen A Beers & Mark S Cragg, 2022, Journal of Experimental and Clinical Cancer Research, 41(131), 131
DOI: 10.1186/s13046-022-02294-5
Type: article
On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation
Joshua M. Sopp, Shirley J. Peters, Tania F. Rowley, Robert J. Oldham, Sonya James, Ian Mockridge, Ruth R. French, Alison Turner, Stephen A. Beers, David P. Humphreys & Mark S. Cragg, 2021, Communications Biology, 4(1)
DOI: 10.1038/s42003-021-02513-3
Type: article
TNF receptor agonists induce distinct receptor clusters to mediate differential agonistic activity
Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H. T.Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Martin J. Glennie & Mark S. Cragg, 2021, Communications Biology, 4(1), 772
DOI: 10.1038/s42003-021-02309-5
Type: article
Activation of GABA(A) receptors inhibits T cell proliferation
Emma L. Sparrow, Sonya James, Khiyam Hussain, Stephen Beers, Mark Cragg & Yury Bogdanov, 2021, PLoS ONE, 16(5 May)
DOI: 10.1371/journal.pone.0251632
Type: article
Immune characterization of pre-clinical murine models of neuroblastoma
Emily Webb, Silvia Lanati, Carol Wareham, Alistair Easton, Stuart N. Dunn, Tatyana Inzhelevskaya, Freja M. Sadler, Sonya James, Margaret Ashton-Key, Mark Cragg, Stephen Beers & Juliet Gray, 2020, Scientific Reports, 10(1)
DOI: 10.1038/s41598-020-73695-9
Type: article