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Chemical Biology, Diagnostics and Therapeutics
About
The Chemical Biology, Diagnostics and Therapeutics group has been replaced by the Organic and Biological Chemistry group.
Organic and Biological Chemistry group page
Our group's research across both chemistry and biology means we are multidisciplinary by nature. We investigate the properties of a wide range of biomolecules, including DNA, proteins, lipids and carbohydrates. These can range from small synthetic models to biologically-derived macromolecular (large molecule) complexes.
We regularly work in collaboration within the University of Southampton, with other institutions or with industrial partners.
Our current research projects include:
- enzyme catalysis
- protein-protein interactions
- post-translational modifications
- lipidomics
The place to fast-track medicines that change lives
Southampton spin-out company Curve Therapeutics has pioneered a faster, smarter way to discover new therapies for complex diseases such as cancer.
People, projects and publications
People
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Doctor Simon Lane
Research FellowEmail: simon.lane@soton.ac.uk -
Professor Sumeet Mahajan
Professor of Molecular Biophotonics & ImagingNew chemical biology methods based on Raman spectroscopy and label-free imaging
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Doctor Ysobel Baker
Royal Society University Research FellowDNA chemistry
Nucleic acid chemistry
Nucleic acid therapeutics
Accepting applications from PhD studentsEmail: Y.R.Baker@soton.ac.uk
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Research projects
Label-free Multimodal Imaging Platform for Detection of Biofilms
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Low Cost Nanowire Diagnostic Platform
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Mahajan - Transformative Healthcare 2050
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Mechanically Interlocked Oligonucleotides: Properties and Applications
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New Reagents for Protein Modification
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OrganVision - EU funded FET Open grant under European Union’s Horizon-2020
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Pepetidomimetic inhibitors of HER2 positive breast cancer
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Protein-gold Nanoclusters for Highly Sensitive Label-free Cellular Imaging
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S Lee - MRC-KHIDI UK-Korea Partnering Award 2016
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S Lee - Seed Award in Science - Wellcome Trust
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Publications
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We research the development of chemistry-driven approaches to modulate proteins’ physiological activity in a wide sense, with the ultimate goal to deliver new tools to study proteins’ function in living systems.