Publications

Browse our publications catalogue to learn about our research.

A longitudinal study of the 5xFAD mouse retina delineates Amyloid beta (Ab)-mediated retinal pathology from age-related changes

Savannah A. Lynn, Sudha Priya Soundara Pandi, Aida Sanchez‑Bretano, Anna Marie Muir, Lidia Parker, David S. Chatelet, Tutte Newall, Jennifer A. Scott, Eloise Keeling, Neil R. Smyth, Jay E. Self, Andrew J. Lotery, Helena Lee & J. Arjuna Ratnayaka, 2025, Alzheimer's Research & Therapy, 17(1)

DOI: 10.1186/s13195-025-01784-w

Type: article

CyPOS; a novel pH-sensitive conjugate for investigation of lysosomal physiology in retinal pigment epithelial (RPE) cells

Charles Ellis, David A. Johnston, David A. Tumbarello, Louise C. Serpell & J. Arjuna Ratnayaka, 2025, Investigative Ophthalmology & Visual Science, 66(8)

Type: conference

Early life pre-disposition to diet-induced retinal pathology

Anna Marie Muir, Savannah A. Lynn, Eloise Keeling, Helen Griffiths, Sandrine Willaime-Morawek, Neil R. Smyth, Helena Lee, Andrew J. Lotery & J. Arjuna Ratnayaka, 2025, Investigative Ophthalmology & Visual Science, 66(8)

Type: conference

Studies in the 5xFAD mouse retina reveal chronic Amyloid-beta mediated effects, providing new insights into complex retinopathies

J. Arjuna Ratnayaka, Savannah A. Lynn, Sudha Priya Soundara Pandi, Aida Sanchez-Bretano, Anna Marie Muir, Lidia Parker, David S. Chatelet, Tutte Newall, Eloise Keeling, Neil R. Smyth, James E. Self, Helena Lee, Andrew J. Lotery & Jenny A. Scott, 2025, Investigative Ophthalmology & Visual Science, 66(8)

Type: conference

Bridging the language gap - A call for the wider use of Human phenotype ontology by non-geneticist clinicians when requesting genomic tests

Larissa Ange Tchuisseu-Kwangoua, Joseph Kamtchum-Tatuene, Cedrik Tekendo-Ngongang, Reuben Pengelly & Jay Self, 2023, European Journal of Medical Genetics, 66(2)

DOI: 10.1016/j.ejmg.2022.104679

Type: article

Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism

Aida Sanchez-Bretano, Eloise Keeling, Jennifer A. Scott, Savannah A. Lynn, Sudha Priya Soundara-Pandi, Sarah L. Macdonald, Tutte Newall, Helen Griffiths, Andrew J. Lotery, J. Arjuna Ratnayaka, Jay E. Self & Helena Lee, 2023, Scientific Reports, 13

DOI: 10.1038/s41598-023-44373-3

Type: article

The orphan drug for Acanthamoeba keratitis (ODAK) trial: PHMB 0.08% (polihexanide) and placebo versus PHMB 0.02% and propamidine 0.1%

John K.G. Dart, Vincenzo Papa, Paolo Rama, Karl Anders Knutsson, Saj Ahmad, Scott Hau, Sara Sanchez, Antonella Franch, Federica Birattari, Pia Leon, Adriano Fasolo, Ewa Mrukwa Kominek, Katarzyna Jadczyk-Sorek, Fiona Carley, Parwez Hossain & Darwin C. Minassian, 2023, Ophthalmology

DOI: 10.1016/j.ophtha.2023.09.031

Type: article