Publications

Explore our research outputs and impact in-depth.

Research outputs

Engineering a HER2-specific antibody–drug conjugate to increase lysosomal delivery and therapeutic efficacy

Jeffrey C. Kang, Wei Sun, Priyanka Khare, Mostafa Karimi, Xiaoli Wang, Yang Shen, R.J. Ober & E. Sally Ward, 2019, Nature Biotechnology, 37(5), 523-526

DOI: 10.1038/s41587-019-0073-7

Type: article

Resolution limit of image analysis algorithms

Edward A.K. Cohen, Anish V. Abraham, Sreevidhya Ramakrishnan & Raimund J. Ober, 2019, Nature Communications, 10

DOI: 10.1038/s41467-019-08689-x

Type: article

The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness

Daisy Melandri, Iva Zlatareva, Raphaël A G Chaleil, Robin J. Dart, Andrew Chancellor, Oliver Nussbaumer, Oxana Polyakova, Natalie A. Roberts, Daniela Wesch, Dieter Kabelitz, Peter M. Irving, Susan John, Salah Mansour, Paul A. Bates, Pierre Vantourout & Adrian C. Hayday, 2018, Nature Immunology, 19(12), 1352–1365

DOI: 10.1038/s41590-018-0253-5

Type: article

Pan-cancer deconvolution of tumour composition using DNA methylation

Ankur Chakravarthy, Andrew Furness, Kroopa Joshi, Ehsan Ghorani, Kirsty Ford, Matthew J. Ward, Emma V. King, Matt Lechner, Teresa Marafioti, Sergio A. Quezada, Gareth J Thomas, Andrew Feber & Tim Fenton, 2018, Nature Communications, 9

DOI: 10.1038/s41467-018-05570-1

Type: article

PD-1 blockade and CD27 stimulation activate distinct transcriptional programs that synergize for CD8+ T-cell driven anti-tumor immunity

Sarah Buchan, Mohannad Fallatah, Stephen Thirdborough, Vadim Y. Taraban, Anne Rogel, Lawrence J. Thomas, Christine Penfold, Li-Zhen He, Michael Curran, Tibor Keler & Aymen Al-Shamkhani, 2018, Clinical Cancer Research, 24(10), 2383-2394

DOI: 10.1158/1078-0432.CCR-17-3057

Type: article

CONFIRM

Dean A. Fennell, Emma Kirkpatrick, Kelly Cozens, Mavis Nye, Jason Lester, Gerard Hanna, Nicola Steele, Peter Szlosarek, Sarah Danson, Joanne Lord, Christian Ottensmeier, Daniel Barnes, Stephanie Hill, Michail Kalevras, Thomas Maishman & Gareth Griffiths, 2018, Trials, 19(233), 1-10

DOI: 10.1186/s13063-018-2602-y

Type: article

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Mohammed M. Naiyer, Sorcha A. Cassidy, Andrea Magri, Vanessa Cowton, Kevin Chen, Salah Mansour, Hariklia Kranidioti, Berenice Mbiribindi , Pauline Rettman, Scott Harris, Liam J. Fanning, Arend Mulder, Franz H.J. Claas, Andrew D. Davidson, Arvind H. Patel, Marco A. Purbhoo & Salim I. Khakoo, 2017, Science immunology, 2(15)

DOI: 10.1126/sciimmunol.aal5296

Type: article