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Research project

Dr P Howarth: 'Wessex severe asthma cohort'

Staff

Other researchers

Emeritus Professor Donna Davies

Research interests
  • Mechanisms of lung diseases
  • Viral-induced exacerbations of lung disease
  • Asthma
Connect with Donna

Email: D.E.Davies@soton.ac.uk

Professor Ratko Djukanovic

Professor of Medicine
Research interests
  • Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where hi…
  • Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the …
  • Stratification of asthma into clinical phenotypes and mechanism-based endotypes: Professor Dj…
Connect with Ratko

Email: rd1@soton.ac.uk

Research outputs

Response [to SpD letter]
2016, Chest, 150(2), 474
DOI: 10.1016/j.chest.2016.05.033
Type: letterEditorial
Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life
Elizabeth R. Davies, Joanne F. Kelly, Peter H. Howarth, David Wilson, Stephen Holgate, Donna E. Davies, Jeffrey A. Whitsett & Hans Michael Haitchi, 2016, JCI Insight, 1(11), 1-16
DOI: 10.1172/jci.insight.87632
Type: article
Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1
Timothy Hinks, T. Brown, L.C. Lau, H. Rupani, Clair Barber, S. Elliott, J.A. Ward, J. Ono, S. Ohta, K. Izuhara, R. Djukanovic, R.J. Kurukulaaratchy, A. Chauhan & P. Howarth, 2016, Journal of Allergy and Clinical Immunology, 138(1), 61-75
DOI: 10.1016/j.jaci.2015.11.020
Type: article
Toll-like receptor 7 is reduced in severe asthma and linked to altered microRNA profile
2016, American Journal of Respiratory and Critical Care Medicine, 194(1), 26-37
DOI: 10.1164/rccm.201502-0280OC
Type: article
IL-1alpha mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit
Alison R. Hill, Jess E. Donaldson, Cornelia Blume, Natalie Smithers, Liku Tezera, Kamran Tariq, Patrick Dennison, Hitasha Rupani, Matthew J. Edwards, Peter H. Howarth, Chris Grainge, Donna E. Davies & Emily J. Swindle, 2016, Tissue Barriers, 4(3), 1-12
DOI: 10.1080/21688370.2016.1206378
Type: article
Airway surfactant protein D deficiency in adults with severe asthma
2016, Chest, 149(5), 1165-1172
DOI: 10.1016/j.chest.2015.11.012
Type: article
Mechanical strain causes adaptive change in bronchial fibroblasts enhancing profibrotic and inflammatory responses
Wiparat Manuyakorn, David Smart, Fabio Bucchieri, Hans Haitchi, Stephen Holgate, Peter Howarth & Donna Davies, 2016, PLoS ONE, 11(4), 1-16
DOI: 10.1371/journal.pone.0153926
Type: article