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Research project

Dr P Howarth: 'Wessex severe asthma cohort'

Staff

Other researchers

Emeritus Professor Donna Davies

Research interests
  • Mechanisms of lung diseases
  • Viral-induced exacerbations of lung disease
  • Asthma
Connect with Donna

Email: D.E.Davies@soton.ac.uk

Professor Ratko Djukanovic

Professor of Medicine
Research interests
  • Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where hi…
  • Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the …
  • Stratification of asthma into clinical phenotypes and mechanism-based endotypes: Professor Dj…
Connect with Ratko

Email: rd1@soton.ac.uk

Research outputs

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations
Maaike De Vries, N. Bedke, N.P. Smithers, M. Loxham, P.H. Howarth, M.C. Nawijn & D.E. Davies, 2016, European Respiratory Journal, 47(3), 783-791
DOI: 10.1183/13993003.00171-2015
Type: article
Microbes and asthma opportunities for intervention
2016, Journal of Allergy and Clinical Immunology, 137(3), 690-697
DOI: 10.1016/j.jaci.2016.01.004
Type: article
temperature-controlled laminar airflow in severe asthmas for exacerbation reduction (The LASER Trial)
W. Storrar, C. Fogg, T. Brown, P. Dennison, L.M. Yu, A. Dewey, R. Luengo-Fernandez, T. Dean, N. Rahman, A. Mansur, P.H. Howarth, P. Bradding & A.J. Chauhan, 2016, Trials, 17(15), 1-13
DOI: 10.1186/s13063-015-1134-y
Type: article
Innate and adaptive T cells in asthmatic patients
Timothy Hinks, Xiaoying Zhou, Karl J. Staples, Borislav D. Dimitrov, Alexander Manta, Tanya Petrossian, Pek Y. Lum, Caroline G. Smith, Jon A. Ward, Peter H. Howarth, Andrew F. Walls, Stephan D. Gadola & Ratko Djukanović, 2015, Journal of Allergy and Clinical Immunology, 136(2), 323-333
DOI: 10.1016/j.jaci.2015.01.014
Type: article
Multidimensional endotypes of asthma
Timothy Hinks, Xiaoying Zhou, Karl Staples, Borislav Dimitrov, Alexander Manta, Tanya Petrossian, Pek Lum, Caroline Smith, Jon Ward, Peter Howarth, Andrew Walls, Stephan D. Gadola & Ratko Djukanović, 2015, The Lancet, 385(Supplement 1), S42
DOI: 10.1016/S0140-6736(15)60357-9
Type: article
A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells
Rocio T. Martinez-Nunez, Victor P. Bondanese, Fethi Louafi, Ana S. Francisco-Garcia, Hitasha Rupani, Nicole Bedke, Stephen Holgate, Peter H. Howarth, Donna E. Davies & Tilman Sanchez-Elsner, 2014, PLoS ONE, 9(10), e111659
DOI: 10.1371/journal.pone.0111659
Type: article
Asthmatic and normal respiratory epithelial cells respond differently to mechanical apical stress
Christopher Grainge, Patrick Dennison, Laurie Lau, Donna Davies & Peter Howarth, 2014, American Journal of Respiratory and Critical Care Medicine, 190(4), 477-480
DOI: 10.1164/rccm.201401-0107LE
Type: article