Dr P Howarth: 'Wessex severe asthma cohort'

Staff

Other researchers

Emeritus Professor Donna Davies

Research interests

Mechanisms of lung diseases
Viral-induced exacerbations of lung disease
Asthma

Connect with Donna

Email: D.E.Davies@soton.ac.uk

Professor Ratko Djukanovic

Professor of Medicine

Research interests

Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where hi…
Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the …
Stratification of asthma into clinical phenotypes and mechanism-based endotypes: Professor Dj…

Connect with Ratko

Email: rd1@soton.ac.uk

Research outputs

TNF-? mediated bronchial barrier disruption and regulation by src-family kinase activation

Michelle A. Hardyman, Emily Wilkinson, Emma Martin, Nivenka P. Jayasekera, Cornelia Blume, Emily J. Swindle, Neil Gozzard, Stephen T. Holgate, Peter H. Howarth, Donna E. Davies & Jane E. Collins, 2013, Journal of Allergy and Clinical Immunology, 132(3), 665-675.e8

DOI: 10.1016/j.jaci.2013.03.005

Type: article

CaMKII is essential for the proasthmatic effects of oxidation

Philip N. Sanders, Olha M. Koval, Omar A. Jaffer, Anand M. Prasad, Thomas R. Businga, Jason A. Scott, Patrick J. Hayden, Elizabeth D. Luczak, David D. Dickey, Chantal Allamargot, Alicia K. Olivier, David K. Meyerholz, Alfred J. Robison, Danny G. Winder, Timothy S. Blackwell, Ryszard Dworski, David Sammut, Brett A. Wagner, Garry R. Buettner, Robert M. Pope, Francis J. Miller, Megan E. Dibbern, Hans Michael Haitchi, Peter J. Mohler, Peter H. Howarth, Joseph Zabner, Joel N. Kline, Isabella M. Grumbach & Mark E. Anderson, 2013, Science Translational Medicine, 5(195), 195ra97

DOI: 10.1126/scitranslmed.3006135

Type: article

Evaluation of a rapid lateral flow immunoassay for Staphylococcus aureus detection in respiratory samples

2013, Diagnostic Microbiology and Infectious Disease, 75(1), 28-36

DOI: 10.1016/j.diagmicrobio.2012.09.011

Type: article

Case series reporting the effectiveness of mycophenolate mofetil in treatment-resistant asthma

Christopher L. Grainge, N.P. Jayasekera, Patrick Dennison, Hitasha Rupani, Ramesh J. Kurukulaaratchy & P. Howarth, 2013, European Respiratory Journal, 42, 1134-1137

DOI: 10.1183/09031936.00026413

Type: article

Barrier responses of human bronchial epithelial cells to grass pollen exposure

Cornelia Blume, Emily J. Swindle, Patrick Dennison, Nivenka P. Jayasekera, Sarah Dudley, Phillip Monk, Heidrun Behrendt, Carsten B. Schmidt-Weber, Stephen T. Holgate, Peter H. Howarth, Claudia Traidl-Hoffmann & Donna E. Davies, 2012, European Respiratory Journal

DOI: 10.1183/09031936.00075612

Type: article

Genome-wide association study to identify genetic determinants of severe asthma

Y. I. Wan, N. R. G. Shrine, M. Soler Artigas, L. V. Wain, J. D. Blakey, M. F. Moffatt, A. Bush, K. F. Chung, W. O. C. M. Cookson, D. P. Strachan, L. Heaney, B. A. H. Al-Momani, A. H. Mansur, S. Manney, N. C. Thomson, R. Chaudhuri, C. E. Brightling, M. Bafadhel, A. Singapuri, R. Niven, A. Simpson, J. W. Holloway, P. H. Howarth, J. Hui, A. W. Musk, A. L. James, M. A. Brown, S. Baltic, M. A. R. Ferreira, P. J. Thompson, M. D. Tobin, I. Sayers & I. P. Hall, 2012, Thorax, 67(9), 762-768

DOI: 10.1136/thoraxjnl-2011-201262

Type: article

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

2012, The Lancet, 380(9842), 651-659

DOI: 10.1016/S0140-6736(12)60988-X

Type: article