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Research project

Dr M Christodoulides - The Adhesin Complex Protein (ACP) of Neisseria meningitidis

Staff

Lead researchers

Professor Myron Christodoulides

Professor of Bacteriology
Connect with Myron

Email: M.Christodoulides@soton.ac.uk

Research outputs

Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus
Maria Victoria Humbert, Alexandra Jackson, Christian M. Orr, Ivo Tews & Myron Christodoulides, 2019, Scientific Reports, 9(1), 1-14
DOI: 10.1038/s41598-019-46506-z
Type: article
Structure of the recombinant Neisseria gonorrhoeae adhesin complex protein (rNg-ACP) and generation of murine antibodies with bactericidal activity against gonococci
Hannia, Liliana Almonacid Mendoza, Maria Humbert, Aiste Dijokaite, David Cleary, Yiwen Soo, Miao-chiu Hung, Christian M. Orr, Ivo Tews & Moritz M. Machelett, 2018, mSphere, 10(3), 1-25
DOI: 10.1128/mSphere.00331-18
Type: article
Neisseria gonorrhoeae employs two protein inhibitors to evade killing by human lysozyme
Stephanie A. Ragland, Maria V. Humbert, Myron Christodoulides & Alison K. Criss, 2018, PLOS Pathogens, 14(7)
DOI: 10.1371/journal.ppat.1007080
Type: article
Immunization with recombinant truncated Neisseria meningitidis-Macrophage Infectivity Potentiator (rT-Nm-MIP) protein induces murine antibodies that are cross-reactive and bactericidal for Neisseria gonorrhoeae
Maria Humbert & Myron Christodoulides, 2018, Vaccine
DOI: 10.1016/j.vaccine.2018.05.069
Type: article
Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor.
Maria Humbert, Amaka Awanye, Li Lian, Jeremy Derrick & Myron Christodoulides, 2017, PLOS Pathogens, 13(6)
DOI: 10.1371/journal.ppat.1006448
Type: article
Novel approaches to Neisseria meningitidis vaccine design
Myron Christodoulides & John Heckels, 2017, Pathogens and Disease, 75(3)
DOI: 10.1093/femspd/ftx033
Type: article
Vaccine potential of bacterial macrophage infectivity potentiator (MIP)-like peptidyl prolyl cis/trans isomerase (PPIase) proteins
María Victoria Humbert, Hannia L. Almonacid Mendoza, Alexandra C. Jackson, Miao-Chiu Hung, Magdalena K. Bielecka, John E. Heckels & Myron Christodoulides, 2015, Expert Review of Vaccines, 14(12), 1633-49
DOI: 10.1586/14760584.2015.1095638
Type: review